Facts About Anthrax
for Consumers and Livestock Producers

Recent cases of anthrax among humans have raised public concern about the disease and its potential as a weapon of biological warfare. In response to these concerns, University of Missouri Extension scientists have compiled answers to some common questions about this rare disease.

Q. What is anthrax?

Anthrax is an acute infectious disease caused by the spore-forming bacterium, Bacillus anthracis. In the United States, anthrax is rare among livestock, and even rarer among humans. Until recent cases in Florida, only one other human case (in a North Dakota farmer handling sick livestock in 2000) has been identified in the United States in at least 15 years.

 

Anthrax most commonly occurs in wild and domestic lower vertebrates (cattle, sheep, goats, camels, antelopes and other herbivores), but it can also infect humans exposed to infected animals or tissue from infected animals. All mammals appear to be susceptible to anthrax to some degree, but ruminants — such as cattle, sheep and goats — are the most susceptible and commonly affected, followed by horses and then swine. In ruminants, the disease generally is characterized by sudden death. Ruminants contract the disease primarily through ingestion of soil-borne anthrax spores. Anthrax does not spread by contact among animals.

 

Because anthrax is considered to be a potential agent for use in biological warfare, the U.S. Department of Defense has begun mandatory vaccination of all active duty military personnel who might be involved in conflict.

 

Q: How common is anthrax, and who can get it?

Anthrax is most common in agricultural regions where it occurs in animals. These include South and Central America, southern and eastern Europe, Asia, Africa, the Caribbean and the Middle East. When anthrax affects humans, it is usually due to an occupational exposure to infected animals or their products. Workers who are exposed to dead animals and animal products from other countries where anthrax is more common may become infected with B. anthracis (industrial anthrax). Anthrax in wild livestock has occurred in the United States.

 

Q: How is anthrax transmitted?

Anthrax infection can occur in three forms: cutaneous (skin), inhalation and gastrointestinal. B. anthracis spores can live in soil for many years, and humans can become infected with anthrax by handling products from infected animals or by inhaling anthrax spores from contaminated animal products. Anthrax also can be spread by eating undercooked meat from infected animals. It is rare to find infected animals in the United States.

 

The two Florida cases appear to be from inhaling anthrax spores. Inhalation anthrax is usually fatal. The North Dakota case was cutaneous anthrax, which results from exposure to spores or vegetative cells when the bacterium enters broken skin (e.g., cut, abrasion, insect bite), such as when handling contaminated wool, hides, leather or hair products (especially goat hair) of infected animals. The U.S. Department of Agriculture reports that cutaneous exposure accounts for 95 percent to 98 percent of anthrax cases. According to the Centers for Disease Control, about 20 percent of untreated cases of cutaneous anthrax will result in death. Deaths are rare with appropriate antimicrobial therapy.

 

According to the USDA, no cases of anthrax have ever occurred in the United States due to ingestion of contaminated food or drink. Anthrax should not pose a health hazard to consumers of meat because animals are inspected for disease by federal and state meat inspectors before, during and after slaughter.

 

Q: What are the symptoms of anthrax?

Symptoms of disease vary depending on how the disease was contracted but usually occur within 7 days.

 

Cutaneous: Skin infection begins as a raised itchy bump that resembles an insect bite but within 1-2 days develops into a vesicle and then a painless ulcer, usually 1-3 centimeters in diameter, with a characteristic black, necrotic (dying) area in the center. Lymph glands in the adjacent area may swell.

 

Inhalation: Initial symptoms may resemble a common cold. After several days, the symptoms may progress to severe breathing problems and shock.

 

Intestinal: The intestinal disease form of anthrax may follow the consumption of contaminated meat and is characterized by an acute inflammation of the intestinal tract. Initial signs of nausea, loss of appetite, vomiting and fever are followed by abdominal pain, vomiting of blood and severe diarrhea. Intestinal anthrax results in death in 25 percent to 60 percent of cases.

 

Q: Can anthrax be spread from person to person?

Direct person-to-person spread of anthrax is extremely unlikely to occur. Communicability is not a concern in managing or visiting with patients with inhalational anthrax.

 

Q: How is anthrax diagnosed?

Anthrax is diagnosed by isolating B. anthracis from blood, skin lesions or respiratory secretions, or by measuring specific antibodies in the blood of persons with suspected cases.

 

Q: Is there a treatment for anthrax?

Doctors can prescribe effective antibiotics. To be effective, treatment should be initiated early. If left untreated, the disease can be fatal.

More Information

Centers for Disease Control Anthrax Fact Sheet

U.S. Department of Agriculture Fact Sheet


Richard Randle, randler@missouri.edu
Extension Veterinarian
University of Missouri-Columbia
Last modified: May 12, 2004

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